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When appetite drops, food intake usually drops too, and that often means lower intake of sodium, potassium, and other minerals that help regulate hydration, nerve function, and muscle performance

It's a type of hormone that cells in your intestines release after you eat

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Use with Medications Known to Cause Hypoglycemia Sitagliptin As is typical with other antihyperglycemic agents used in combination with a sulfonylurea, when sitagliptin was used in combination with metformin and a sulfonylurea, a medication known to cause hypoglycemia, the incidence of hypoglycemia was increased over that of placebo in combination with metformin and a sulfonylurea [see Adverse Reactions]

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