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Foundational mechanism paper

For researchers who are also competitive athletes, note that compounds not approved for human use can fall under broad anti-doping categories even where not specifically named

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5-Amino-1MQ Also known as: 5-amino-1-methylquinolinium, NNMTi TL;DR Increases intracellular NAD+ levels via NNMT inhibition (preclinical) Reduces body weight and white adipose mass in diet-induced obese mice Improves grip strength by up to 60% in aged mice when combined with exercise Suppresses lipogenesis in adipocytes without affecting food intake Community-Reported Side EffectsAnecdotal

J Crohns Colitis 2013

Standard therapies possess extensive, long-term safety data and profound cardiovascular benefits that make them the gold standard for initiating treatment