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Since there have been some interesting developments in both the diagnosis and treatment of B12 deficiency, and since B12 deficiency remains so common, this seems like a good opportunity for some updates

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Trypanosomes exhibit several features of eukaryotic cell apoptosis, including loss of mitochondrial membrane potential, cytochrome c release, cell shrinkage, and DNA fragmentation, although the exact mechanisms involved in PCD of trypanosomatids and its biological relevance is still under debate (De Souza et al., 2010

Shukla et al., 2018)

B12 is a water-soluble vitamin with an excellent safety profile