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Nanoscale 6 (12), 68376843 (2014) J.-Z

Glucagon activation helps the body break down stored fat and increases energy expenditure

Klotho, oxidative stress, and mitochondrial damage in kidney disease

however, this is not its intended purpose

ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation

The SUMMIT trial, involving 731 individuals with HFpEF and obesity followed for a median of 104 weeks, revealed a 38% decrease in the composite endpoint of cardiovascular mortality or heart-failure deterioration events (HR: 0.62, 95%CI: 0.41-0.95, P = 0.026), driven primarily by fewer worsening heart-failure events (8.0% vs