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For best results, yes

Heart Palpitations or High Blood Pressure Heart palpitations Increased heart rate Elevated blood pressure Signs and Symptoms of B12 Overdose signs and symptoms of B12 overdose may include: Skin rash or acne Headaches Nausea or diarrhea Anxiety or restlessness Heart palpitations High blood pressure Trouble sleeping How Much Vitamin B12 Is Too Much

AOD-9604 received FDA GRAS (Generally Recognized As Safe) status as a food ingredient in 2007, but this is not drug approval

I am not vegetarian, but am not big on meat, fish and dairy, particularly beef, milk and yoghurts etc

Can supplements help

their skin permeability is low, making it difficult to reach effective concentrations