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Alok Malik, president and business head, India formulations, at Glenmark Pharmaceuticals, said a big challenge in GLP-1 therapies is to ensure patients are able to start and stay on treatment

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Tirzepatide, a dual GLP-1 and GIP receptor agonist, has become a cornerstone treatment for weight loss, with clinical trials showing weight reductions of 20-22% in some participants

In summary, the reaction begins when the thiolate of this cysteine residue nucleophilically attacks the GSH moiety of the glutathionylated protein