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PMCID: PMC4321783

F.AkersC

Weekly dosing protocols are being investigated as alternatives

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These alterations in the tumor ECM induce an increase in its stiffness, typically evaluated using techniques that either require direct contact with the sample (e.g., atomic force microscopy), or measure the tumor mechanical properties in a contact-free manner (e.g., shear wave elastography, magnetic resonance elastography) (Table 3)

AOD9604 may require 0.6% acetic acid solution for reconstitution