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Second, sample sizes in key depression-microbiota studies are frequently small (e.g., n = 23 in Strandwitz et al

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Notably, oxidative stress is linked with the activation of protein kinase C (PKC), which is normally consistent with impaired insulin signaling and tissue damage in experimental models of diabetes (King and Brownlee, 1996)

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Patients should follow a systematic rotation pattern and maintain a written log to track application sites and prevent skin complications