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Trials are investigating obesity, overweight with weight-related conditions, type 2 diabetes, knee osteoarthritis pain, moderate-to-severe obstructive sleep apnea, chronic low back pain, cardiovascular and renal outcomes, and metabolic dysfunction-associated steatotic liver disease

In 1970, the successful application of this method for determination of the diffusion coefficients of haemocyanin at low concentration was reported by Foord et al

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