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Liu L, Li T, Li F, Zhao X, Zhang R, Liu J, et al

Initially developed as a diabetes medication , Semaglutide was later approved for weight loss after clinical trials revealed its benefits in reducing body weight

Caspase-3-dependent proteolytic cleavage of tau causes neurofibrillary tangles and results in cognitive impairment during normal aging

Getting approval for GLP-1 medications through traditional insurance can take weeks and often requires documented obesity or type 2 diabetes diagnoses

Meanwhile, in late 2025, Danish pharmaceutical company Novo Nordisk (the makers of Ozempic and Wegovy) announced they had found no reduction in Alzheimers progression from early trials of semaglutide