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The potential for hepatotoxicity develops when large doses of acetaminophen saturate the typical conjugation pathways and overwhelm available glutathione stores, leading to reduced clearance of the toxic metabolite

13 If cellular and mitochondrial membranes are damaged from exposure to toxins, infections, and other causes of oxidative damage, how can the membranes be repaired

2008 Oct;42(10):1481-5

This age-related reduction correlates with decreased tissue repair capacity and is hypothesised to contribute to age-related hair thinning and follicle miniaturisation

NAC contains a highly reactive sulfhydryl group (SH), which gives it the direct ability to bind, or chelate, to certain heavy metals

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