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When to Seek Medical Advice Anyone considering or who has already used retatrutide should consult a GP or specialist, particularly if they have a history of pancreatitis, gallbladder disease, diabetes, or cardiovascular or renal conditions

10.1016/0024-3205(81)90045-X 159 ShankR

Endocrinology 151(3):865875

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It means the risk is unquantified