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The subcutaneous route exists for researchers using a lyophilized vial format, but it is limited to small doses

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However, sensitive skin users are advised to conduct a patch test first, starting with low concentrations (below 0.5%) to build tolerance

Benefits: *increases energy *increases B12 intake for vegans *increases mood *decreases depression symptoms Risks when deficient: Watch Video *increases dementia *decreases visual acuity Vitamin B12 is also used for various health and wellness applications like boosting red blood cell production, and helping to regulate sleep, mood, and appetite cycles

(2016) 111:S271