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Effects of alpha-lipoic acid supplementation on C-reactive protein level: A systematic review and meta-analysis of randomized controlled clinical trials

Mechanistically, acetyl-CoA, a derivative of BCKAs, inhibits the interaction between PR domain-containing protein 16 (PRDM16) and peroxisome proliferator-activated receptor- (PPAR-) by acetylating the k915 site of PRDM16 to maintain WAT characteristics

However, it is not as effective as the supplement alpha-lipoic acid

It assists the organisation to be able to use more fat as a source of power, which conserves glycogen and allows the body to sustain more workouts

Schulz C, Vezzani C, Kroemer NB