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Autophagy is a process by which cells in vivo produce autophagic vesicles to engulf damaged organelles and macromolecules in the presence of nutrient deficiency or oxidative stress and use lysosomes to degrade them, thereby maintaining the stability of the intracellular environment [90]

LCMS analysis Liquid chromatography-mass spectrometry (LCMS) analysis was conducted with a Q-Exactive quadrupole-Orbitrap mass spectrometer (Thermo Fisher Scientific, USA) coupled with a Dionex Ultimate 3000 nano-UPLC system

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Representative images of PVN GLP-1R DVC neurons using the strategy depicted in ( a ).(n = 3 mice) c

Epithalon is a synthetic tetrapeptide commonly discussed in longevity research contexts around telomere biology, cellular ageing, and circadian rhythm support