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Because retatrutide has not yet received regulatory authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA), it is not legally available for prescription in the UK outside of authorised clinical trials

References: Baggio LL, Drucker DJ (2007): Biology of incretins: GLP-1 and GIP

Circulating plasma GLP-1 levels rise from approximately 510 pmol/L in the fasted state to 1550 pmol/L in the postprandial state, with peak levels depending on meal composition, caloric density, and rate of gastric emptying

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