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Sublingual or buccal administration increases bioavailability to approximately 70%, while intranasal delivery

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Breakthroughs in multi-omics technologies have confirmed that gut microbiota and their metabolites play a crucial role in regulating the pathological progression of IBD ( This review focuses on describing local intestinal iron metabolism, the regulation of iron homeostasis, and host-microbiota interactions based on current research findings, while also elucidating the underlying molecular mechanism of metabolite-modulated ferroptosis plasticity

Body composition assessment at week 12 provides the first objective measure of whether the combination is producing the hypothesized benefits