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Prescription medications should come through regulated healthcare pathways, with proper medical assessment, safe supply and ongoing support

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Understanding these differences allows researchers to make informed decisions about which formulation best serves their specific protocols

Biol Pharm Bull 25:945953 Nakanishi S, Nakajima Y, Masu M, Ueda Y, Nakahara K, Watanabe D, Yamaguchi S, Kawabata S, Okada M (1998) Glutamate receptors: brain function and signal transduction

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Since effective LDL-C reduction is the most important method to improve the prognosis in HoFH, intensive treatment should be carried out, involving all available interventions, i.e., high doses of potent statins, ezetimibe, PCSK9 inhibitors, and LDL apheresis [265, 284]