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Saxagliptin In a randomized, double-blind, placebo-controlled, 4-way crossover, active comparator study using moxifloxacin in 40 healthy subjects, saxagliptin was not associated with clinically meaningful prolongation of the QTc interval or heart rate at daily doses up to 40 mg (8 times the recommended maximum daily dose)

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oral supplementation might not have the same effects [18, 20, 22]

Other large clinical trials have found the drugs reduce the risk of chronic kidney disease progression and improve outcomes in several other age-related conditions, suggesting their benefits extend well beyond diabetes and weight loss

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It is statistically significant and the consequences of hypotension can be terrible