New @Nature A quintuple [GLP-1 + 4 other] receptor agonist drug that exceeds effects of the dual receptor (GLP-1 and GIP, tirzepatide) in the experimental model vs diabetes and obesity (in case you thought a dual receptor was max effect, as also seen with retatrutide, a triple pic.twitter.com/bvjCbj5Y6P - Eric Topol (@EricTopol) April 29, 2026 Journal reference: Liskiewicz, D., Novikoff, A., Khalil, A
When combined with other prescription drugs, these powerful peptides can create unpredictable effects that require careful medical oversight
1 You may have heard of Ozempic, Monjauro, Zepbound or Wegovyall brand names for different types of GLP-1 drugs
Discuss with your physician before taking if you have a medical condition or are taking any prescription medications
When appropriate, peptides can be used as part of a broader weight loss strategy to help optimize results and support overall wellness
It contributes to the structure and stability of HDL particles and has a role in lipid metabolism