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doi: 10.1038/ng787 24 BrouwerJ

The vitamins exist to support enzymatic pathways that use those amino acids, not to replace them

SIRT3 has been implicated in various metabolic-related diseases, through directly deacetylating multiple enzymes in mitochondrial metabolism [53]

In fact, electrophysiological studies have linked elevated Hcy levels in LDopa-treated patients to axonal loss in the sural nerve and a tendency towards weight loss among these patients (Cossu et al

Ren Z, Sun S, Sun R, Cui G, Hong L, Rao B, et al

Timing matters too: injecting at night before bed may reduce awareness of side effects, and some patients tolerate a slightly lower weekly dose better than the standard protocol