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The same effect of liraglutide was revealed in another study in patients with diabetes and hypertension but without renal impairment 27

doi: 10.1093/ecco-jcc/jjx008 104 MartensE

In other settings (like surgical cohorts), it may appear more often simply because more tissue is being sampled and examined carefully

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Chronic exposure to peroxisome proliferators in rodents leads to deposition of lipofuscin and eventually to liver tumors, most probably a consequence of oxidative stress leading to DNA damage (Evans and Lake 1998)