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261 In addition, the H19 sponge cell miR-130a induces PPAR nuclear translocation, thereby activating the transcription of adipogenic genes like those encoding acetyl coenzyme a carboxylase 1 (ACC1), fatty acid synthase (FAS), and cytochrome c oxidase (SCO1), thereby promoting intracellular lipid accumulation

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Intriguingly, when combined with other compounds, the anticancer efficacy of melatonin is enhanced synergistically

The primary molecular mechanism of TB-500 involves regulation of actin dynamics through its high-affinity binding to monomeric G-actin