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A less common but possible side effect, due to its breakdown into trimethylamine

Mechanistic link between vitamin B12 and Alzheimers disease

The resulting ranked paths highlight likely molecular routes connecting sources to the target within the network

The activation of other pro-survival signaling pathways, such as the PI3K/Akt, MAPK, and NF-kB pathways, as well as the regulation of DNA repair mechanisms (e.g., ATM/ATR and Chk1/Chk2 pathways), also play critical roles in paclitaxel resistance