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These effects may arise from the peptides capacity to modulate local growth factors and attenuate inflammatory pathways

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Inhibition of key ferroptosis regulators like acyl coenzyme ACSL4, GPX4, and Nrf2 may lead to unintended consequences, including disruptions to cellular homeostasis, thereby posing potential risks to therapeutic safety

DPP-4i treatment significantly increases proximal tubular cell viability and reduces ROS production