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Many anticonvulsant drugs act by increasing GABA in the synapse.[ref] Genetic variants that decrease the function of the GABA-A receptors essentially decreasing GABA inhibition are linked to an increased risk of epileptic seizures.[ref] Insomnia: Brain GABA levels were studied in people with primary insomnia who were not on medication

revealed that adding atorvastatin (20 mg/day, P.O for 4 weeks) reduced plasma MDA while improving the functional capacity assessed via a 6-minute walk test in patients with chronic heart failure (CHD) [228]

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