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Patients should not adjust their dosing schedule without consulting their healthcare provider

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There is no reliable way to predict individual response before initiating treatment, making therapeutic trials necessary

This makes them useful to manage type 2 diabetes and obesity

A macrocyclic peptide that serves as a cocrystallization ligand and inhibits the function of a MATE family transporter

Gut incretin hormones in identical twins discordant for non-insulin-dependent diabetes mellitus (NIDDM)evidence for decreased glucagon-like peptide 1 secretion during oral glucose ingestion in NIDDM twins