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This discrepancy is not unique to antioxidants

206 Combined administration of shikonin and cisplatin increases Fe 2+ , ROS, and lipid peroxidation (LPO) levels and downregulates GPX4 in ovarian cancer cells, reducing cisplatin resistance by inducing ferroptosis

(PubMed) Ghadirian P, Jain M, Ducic S, Shatenstein B, Morisset R

Stress Management : Implement stress-reduction techniques such as meditation, yoga, or deep-breathing exercises to help lower oxidative stress and support glutathione levels

In epilepsy, this interplay is evident in models such as the lithium-pilocarpine (Li-Pilo) model of SE, which recapitulates key features of epileptogenesis including altered glucose metabolism (Dank et al., 2022) and mitochondrial bioenergetics with increased markers of oxidative damage (Carrasco-Pozo et al., 2015

Often called the "master antioxidant," its job is to neutralize free radicalsunstable molecules that can damage cells and accelerate the signs of aging