|lipid control with single-drug therapy
SGLT2 inhibitorrelated adverse effects, including genital mycotic infections, volume depletion, and rarely ketoacidosis, remain clinically relevant and should be considered when these agents are prescribed as part of combination therapy and importantly, the intrinsic risk of hypoglycemia with combined GLP-1 receptor agonist and SGLT2 inhibitor therapy is low because neither class directly stimulates insulin secretion in a glucose-independent manner and when hypoglycemia occurs, it is more commonly related to concomitant insulin or sulfonylurea use rather than the combination itself [41, 42, 44]
Varisco, PharmD, PhD, an assistant professor in the Department of Pharmaceutical Health Outcomes of Policy and assistant director for Research Development in the Prescription Drug Misuse Education and Research Center at the University of Houston College of Pharmacy
While these bioactive compounds offer numerous health benefits at low doses, high doses or prolonged use can lead to adverse effects, including organ-specific toxicity, pro-oxidant activity, and drug interactions
Others In addition to the above compounds, many other natural medicines potentially protect the myocardium by enhancing the GSH antioxidant system
Inflammation Fighter
