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When to Resume Research: After experiencing a side effect that needed protocol change or temporary discontinuation, decisions about resuming research should be made carefully

N Engl J Med 356(11):11401151 Aubert G, Martin OJ, Horton JL, Lai L, Vega RB, Leone TC, Koves T, Gardell SJ, Krger M, Hoppel CL, Lewandowski ED, Crawford PA, Muoio DM, Kelly DP (2016) The failing heart relies on ketone bodies as a fuel

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A placebo controlled, randomized double-blind phase II study