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Rosen says
Fitty is safe for long-term use designed to build healthy, lasting habits.
For diabetes management, dose adjustments are guided by glycemic control markers, primarily HbA1c and self-monitored blood glucose readings
The STEP 1 trial (Wilding et al., 2021), one of the largest studies on semaglutide, found that 39% of the weight lost over 68 weeks was lean mass
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consideration of dose escalation 6 months : Formal assessment of treatment efficacy according to appropriate criteria: For diabetes (NICE NG28): HbA1c reduction of at least 11 mmol/mol (1.0%) and weight loss of at least 3% For weight management: At least 5% weight loss from baseline on maintenance dose (per SmPC and NICE guidance) Annually thereafter : Ongoing monitoring of metabolic parameters, cardiovascular risk factors, and treatment appropriateness Treatment adjustments may be necessary if: Side effects remain intolerable despite supportive measures Weight loss plateaus before reaching target (may warrant dose increase if not at maximum) Inadequate glycaemic control persists (may require additional diabetes medications) Significant weight loss goals are achieved (maintenance strategies and potential dose reduction) Patients should maintain open communication with their healthcare team, reporting both positive developments and concerns
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