Tirzepatide (The Active Ingredient in Mounjaro and Zepbound) Tirzepatide represents the next evolution in GLP-1 therapy
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Due to mechanical loading, increased body weight is positively correlated with bone mineral density (BMD) and cortical bone formation
Moreover, GLP-1RAs have neuroprotective, anti-infectious, cardiovascular protective, and metabolic regulatory effects, exhibiting good application prospects
[ref] Circadian control of response to GLP-1: Like many hormones, there is a circadian aspect to GLP-1
10,17 GLP-1 receptor stimulation in the arcuate nucleus also improves glycemic control independent of feeding behavior