Gut microbiota dysbiosis mediates the comorbidity of chronic constipation and depression through several intertwined molecular pathways
The gut-liver axis plays a key role in MASLD, with reduced alpha diversity and certain microbial profiles being associated with worse outcomes [35]
tirzepatide) with unique mechanisms of action (GLP-1 vs
This difference may explain why overall cardiovascular outcomes remain favorable despite small increases in resting pulse
In addition to cardio, the patient should be on a regular strength training regimen, which can be performed at home or the gym but includes body weight or gym-style weights to build muscle
When to seek medical advice: Contact your GP if you experience severe abdominal pain (especially if accompanied by vomiting), rectal bleeding, unexplained weight loss, abdominal distension, or absolute constipation (complete inability to pass stool or gas)