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We also found that semaglutide treatment decreased astrogliosis and microgliosis in the dentate gyrus region of the hippocampus

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Available at: Last accessed: 19 June 2026

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"Many people who take these medications have struggled their entire lives with weight and these athletes rarely have." There's also the misconception of potential enhanced performance, a claim Ortiz-Pujols debunks with the reminder that these athletes "have access to personal trainers and personal chefs with hours to train."

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With trials of potential long-term benefits of these medications still ongoing, the jury is out on whether their potential benefit justifies the cost

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However, significant global overexpression of GIP receptors reduced inflammatory markers in mice and prevented obesity [17]

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