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In addition, EAAC1 is mainly localized to the forebrain including the hippocampus and no neurodegeneration was observed during a period of over 12 months in EAAC1 KO mice 74

This is not the same as the dangerous edema associated with serious medical conditions

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Its believed that damage from oxidative stress plays a critical role in memory loss ( Because alpha-lipoic acid is a powerful antioxidant, studies have examined its ability to slow the progression of disorders characterized by memory loss, such as Alzheimers disease

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Therefore, reducing MMP-9 can inhibit glycocalyx degradation, protect the BBB and restore the function of cerebrovascular endothelium