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The Effect of Selective Estrogen Receptor Modulators (SERMs) on the Tamoxifen Resistant Breast Cancer Cells

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The mechanisms behind this increased risk are multifactorial: Iron and Estrogen Synergy: In breast tissue, iron synergizes with estrogen metabolites to generate reactive species, a process intensified in post-menopause when iron stores rise

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Peppelenbosch MP, Spaander MC, Bruno MJ