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The difference between these drugs largely lies in their mechanisms of action

They are more suited for fine-tuning body composition in already-lean individuals

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Compared with SUSTAIN 6, PIONEER 6 included a greater proportion of patients receiving sodium-glucose co-transporter-2 inhibitors (SGLT2is

Medical evaluation and prescription required

The high metabolic rate and high oxygen consumption of brain parenchyma will inevitably lead to the production of a large number of by-products ROS, and may further cause oxidative stress (93)