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Patent protections for semaglutide (Ozempic/Wegovy) expire in 2026 in Canada, India, Brazil and China, opening the door for lower-cost biosimilar generic versions

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Furthermore, autistic individuals often exhibit disturbances in redox signaling, with reduced levels of reduced glutathione and an increase in oxidized glutathione disulfide

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For other 5-HT 4 agonists, including clebopride, cinitapride and mosapride, there is relatively weak evidence to support efficacy [73], and cisapride, which appeared to be effective at relieving symptoms, was withdrawn from the market in 2000 due to concerns about cardiovascular safety [73]