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[DOI] [PubMed] [Google Scholar] 88.Lim M.M., Young L.J

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These include TNF-alpha, IL-1 beta, and IL-6, all of which drive joint destruction in inflammatory arthritis

By targeting NNMTan enzyme highly expressed in adipose tissue and linked to insulin resistancethis compound allows researchers to explore how shifting cellular metabolism away from fat storage toward energy utilization can impact systemic health