300-OR: Beneficial Effect of the Combination Therapy of Cagrilintide, a Dual Amylin/Calcitonin Agonist, and Tirzepatide, a Dual GLP-1/GIP Agonist, on Body Weight Loss in Obese Rats
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Central to this axis is the gut microbiota, which plays a pivotal role in maintaining homeostasis across the gastrointestinal, neurological, and renal systems
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Specific Improvements: Cagrilintide suppresses the nuclear factor-kappa B (NF-B) pathway, reducing the synthesis and release of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-) and interleukin-6 (IL-6)
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