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When the body doesnt get enough water, it cant transport electrolytes as efficiently, making muscle cramps more likely

Most commonly, users report mild-to-moderate digestive issues such as nausea, diarrhea, or constipation, especially when starting the therapy

"Once-Weekly Semaglutide in Adults with Overweight or Obesity." NEJM 2021 Jastreboff AM, et al

Quick Answer: Tirzepatide may cause or worsen GERD in some patients, though the relationship is not fully established and GERD is not prominently featured in FDA labeling

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