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The Journal of the Pakistan Medical Association

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Serious but rare risks include hypoglycemia (low blood sugar), acute pancreatitis (severe, persistent abdominal pain often with vomiting), acute gallbladder disease (sudden right-upper abdominal pain that may radiate to the shoulder), non-arteritic anterior ischemic optic neuropathy (sudden, potentially permanent vision loss), mood changes, and severe allergic reactions with breathing difficulty or swelling of the lips, tongue, or throat

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The researchers assessed kidney oxygenation (R2*) using blood oxygenation leveldependent MRI, and they assessed mean global kidney perfusion (GKP), renal artery resistive index (RARI), and cortical and medullary estimates of fibrosis (diffusion-weighted imaging for the apparent diffusion coefficient [ADC]) with phase-contrast MRI-measured arterial flow

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Hypoglycaemia Incidence of any hypoglycaemia (defined as plasma glucose 3.9 mmol/l) with tirzepatide did not differ vs placebo (ESM Fig

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