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In this study, metformin effectively suppressed oxidative stress through promoting Nrf2 expression in MIA-induced mouse model (Fig

Although CNTs have poor solubility in both water and organic media, they can be chemically modified to improve their solubility, degradation ability, and drug-loading capacity while reducing toxicity

That said, the combination has not been tested for safety or effect in a human trial, so "can" here means chemically formulated together, not clinically validated

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doi: 10.1007/s00394013-05956 193 BradleyJMOrganCLLeferDJ

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