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Individual responses vary, which is why baseline colitis assessment and close monitoring during the first 48 weeks of treatment are essential

Microdose protocols typically involve taking smaller amounts more frequently, such as dividing the weekly dose into two or three smaller injections

These include pancreatitis (rare but reported in clinical trials and post-marketing surveillance), gallbladder disease, and acute kidney injury (particularly in the setting of severe dehydration from gastrointestinal effects)

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