The second observational study looked at the health records of more than 12,000 people and found that GLP-1s were associated with a lower risk of tumour spread in lung, breast, colorectal and liver cancer by just under 40% to 50% (depending on type), compared with older drugs called gliptins
The FDA said that it will allow compounding pharmacies to continue to make copies of semaglutide for now, which they are usually allowed to do only while the drug is in shortage
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[Accessed on 11 June 2026] Orforglipron, an oral small-molecule GLP-1 receptor agonist for obesity treatment (2025)
However, the convenience of a single morning dose means most researchers prefer once-daily administration, and the clinical data supporting split dosing specifically for AOD 9604 is limited