GLP-1 agonists reduce systolic blood pressure by 3-5 mmHg, improve lipid profiles, and lower progression to cardiovascular events by 26% in high-risk type 2 diabetes patientseffects that appear independent of weight reduction alone
the first step is conjugation of glutamic acid and cysteine, which is catalyzed by glutamate-cysteine ligase and generates -glutamyl-cysteine (-Glu-Cys) and the second step is catalyzed by glutathione synthase, which adds glycine to -Glu-Cys, forming glutathione
It's best to get treated for B12 deficiency anemia and avoid any long-term problems
This allows the glutathione to stay protected as it travels through the digestive system
Chronic stress actually depletes your glutathione stores, working against everything you're trying to accomplish
Interestingly, BPC-157 peptide for gut health is another area of active research