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Hypothesis The authors hypothesized that metformin may partially prevent weight regain after weight loss induced by semaglutide

Intermuscular adipose tissue-derived inflammatory adipokines, exacerbated by aging, obesity, and sedentary behavior, promote both fat accumulation and chronic inflammation within skeletal muscle, driving adipogenic differentiation at the expense of myogenesis and thereby contributing to reduced muscle quality and increased metabolic risk [81]

Once reconstituted, store at 28C

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Researchers often employ controlled handling procedures to support consistency during experimental use