inhibitory glp 1 Complementary Yet Distinct Roles of GLP-1 Receptor Agonists and SGLT2 Inhibitors in Cardiovascular Risk Reduction GLP-1 receptor agonists and next-generation

Do not use with MAO inhibitors

Unlike many fad diets and quick fixes, these medications support sustainable weight loss by addressing the underlying hormonal and metabolic factors

Brand-Name vs Compounded Brand-Name Pens | Josie Compounded (Oral & Injectable) Fixed factory doses | Personalized micro-doses that your provider can raise or lower One delivery form per drug | Choice of daily dissolvable tablet or weekly shot Limited when insurance wont cover | Cash-pay pricing + licensed 503A pharmacies Standard titration schedule | Slow, symptom-based titration for midlife digestion & hormone shifts Why it matters: In menopause, slower digestion and higher medication sensitivity mean easing in gently can be the difference between quitting and succeeding

Cagrilintide 2.4 mg Population: BMI 30, no diabetes Key Results (32 Weeks): Mean Weight Loss: 15.1% with CagriSema (combination) 9.8% with semaglutide 2.4 mg alone 7.7% with cagrilintide 2.4 mg alone Synergy Demonstrated: Combination produced 54% more weight loss than semaglutide alone, 96% more than cagrilintide alone 15% Weight Loss: 53% (CagriSema) vs

Use of the injections started increasing in 2022, followed by "a sharp increase" in 2024

NPJ | Metabolic Health and Disease