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These effects are mediated by: Improved endothelial function and nitric oxide bioavailability Reduced vascular inflammation and oxidative stress Stabilization of atherosclerotic plaque Enhanced cardiac metabolism and mitochondrial efficiency From a longevity standpoint, microdosing may maintain low-grade GLP-1 receptor activation within vascular tissue, supporting arterial flexibility, autonomic tone, and lipid regulation without the gastrointestinal intolerance often limiting high-dose use
Generic calorie apps are useful for database size and macro tracking, but they were not built around GLP-1 days when appetite, food tolerance, side effects, water, protein, and fiber all need to be seen together
The particularly exciting thing about this class of diabetes medications is that, in contrast to many currently available diabetes drugs that address downstream effects, these medications target the root cause of diabetes
Provincial drug plans rarely cover obesity medications
The 2022 ASMBS/IFSO guidelines also recommend surgery be considered for patients with obesity-related health conditions and a BMI of 3034.9. If you are interested in weight loss surgery, but do not qualify because your BMI falls below the current guidelines, you may be eligible for weight loss surgery through a low BMI study conducted by New Jersey Bariatric Center surgeons at Atlantic Healths Overlook Medical Center
Accessed January 21, 2026
