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Footnotes to EPIC's parameters are meaningless window-dressing It is not just customary, but really professionally mandatory, that when veterinary researchers select a particular measurement as the minimum or maximum parameter for qualifying candidate dogs for a study of a new medication (or the new application of an existing drug), the researchers state their reasoning for choosing that measurement and cite the prior published authorities for relying upon it

Lancet 392(10157):15191529 Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JF, Nauck MA, Nissen SE, Pocock S, Poulter NR, Ravn LS, Steinberg WM, Stockner M, Zinman B, Bergenstal RM, Buse JB (2016) LEADER Steering Committee

Tirzepatide 5 mg showed an average weight loss of more than 5% of body weight at the median time of 16 weeks, while 10 and 15 mg took 12.4 weeks to show significant weight changes and glycemic control

2 (2019): 197-208, Y.I

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